The Short Answer
Yes, Thorne is excellent. If you have the budget for it (~$36/month), it is widely considered the "gold standard" of multivitamins. Unlike drugstore brands like Is Centrum Good|Centrum or Is One A Day Good|One A Day, Thorne strictly avoids synthetic fillers, artificial colors, and cheap, poorly absorbed nutrient forms.
The standout feature is bioavailability. Thorne uses the "active" forms of vitamins—like 5-MTHF for folate and Methylcobalamin for B12—which means your body doesn't have to convert them before using them. This is critical for the estimated 40% of people with MTHFR gene mutations who cannot efficiently process standard folic acid.
Why This Matters
Most multivitamins are "expensive urine"—literally. They use cheap forms of nutrients (like Magnesium Oxide or Zinc Oxide) that pass right through your digestive tract unabsorbed. Thorne uses chelated minerals (bound to amino acids) and methylated vitamins, ensuring you actually get what you paid for.
Safety is guaranteed. The supplement industry is notoriously unregulated, but Thorne voluntarily undergoes NSF Certified for Sport testing. This is a rigorous third-party certification that verifies the bottle contains exactly what the label says and is free from over 270 banned substances and contaminants.
What's Actually In Basic Nutrients 2/Day
Thorne's flagship product replaces the standard grocery store ingredient list with premium forms.
- Folate (as L-5-Methyltetrahydrofolate) — The active form of folate. Essential for DNA synthesis and safe for those with MTHFR mutations. Avoids the potential risks of unmetabolized Folic Acid Vs Methylfolate|Folic Acid.
- Vitamin B12 (as Methylcobalamin) — The naturally occurring form of B12. Far superior to Cyanocobalamin Vs Methylcobalamin|Cyanocobalamin, a synthetic form derived from cyanide that your liver must detoxify.
- Zinc (as Bisglycinate Chelate) — A "chelated" mineral bound to glycine. Studies show this form absorbs significantly better than the Zinc Oxide or Gluconate found in cheaper pills.
- Vitamin B6 (as Pyridoxal 5'-Phosphate) — The active "P-5-P" form. While the dosage (20mg) is high compared to the RDA, this form is less likely to cause nerve toxicity than the synthetic Pyridoxine HCl used by competitors.
What to Look For
Green Flags:
- NSF Certified for Sport — The highest standard for purity testing.
- TGA Certified Facility — Manufactured in a facility with an "A" rating from Australia's Therapeutic Goods Administration (known as the world's toughest regulator).
- Clean "Other Ingredients" — Uses simple cellulose and calcium laurate. No Vitamin Fillers|Titanium Dioxide, artificial dyes (Red 40), or hydrogenated oils.
Red Flags:
- The Smell — Real B-vitamins have a distinct, pungent odor. Thorne doesn't use artificial scents to mask this, so the bottle will smell "earthy" or "yeasty." This is normal.
- Neon Yellow Urine — You will pee bright yellow. This is harmless; it's just excess Riboflavin (Vitamin B2) being excreted.
- Price — At $1.20 per day (2 capsules), it is an investment. You are paying for quality assurance and absorption, not marketing.
The Best Options
If you are considering Thorne, here is how their top options stack up.
| Product | Verdict | Best For | Why |
|---|---|---|---|
| Basic Nutrients 2/Day | ✅ | Most People | The gold standard. High potency, covers all bases. |
| Women's Multi 50+ | ✅ | Post-Menopause | Adds Calcium/Magnesium, removes Iron (safer for older adults). |
| Men's Multi 50+ | ✅ | Men over 50 | Tailored nutrient ratios, no iron, high zinc for prostate health. |
| Kids Multi+ | ✅ | Children | Dissolvable disc (no sugar/gummies). See Best Multivitamin Kids. |
The Bottom Line
1. Buy it if you can afford it. If $36/month is within your budget, this is the best nutritional insurance policy you can buy.
2. Take with food. The high zinc and B-vitamin content can cause nausea on an empty stomach. Always take it with a solid meal (breakfast or lunch).
3. Split the dose. The serving size is 2 capsules. For better absorption, take one in the morning and one at lunch/dinner.
FAQ
Why does my pee turn yellow?
That's the Riboflavin (Vitamin B2). Thorne includes 12mg (923% DV), and because B2 is water-soluble and naturally fluorescent yellow, your body excretes what it doesn't immediately use. It is completely harmless.
Is the Vitamin B6 dosage (20mg) toxic?
Likely not. The toxicity threshold for B6 is generally considered to be above 100mg-200mg per day over long periods. Thorne uses Pyridoxal 5'-Phosphate (P5P), the active form, which does not accumulate in the body the same way synthetic Pyridoxine does. However, if you experience tingling in your fingers, stop taking it.
Can I just take one capsule a day?
Yes. Taking one capsule gives you 50% of the amounts listed, which is still a very potent multivitamin (e.g., 10mg B6, 300mcg B12, 1000 IU Vitamin D). This also makes the bottle last two months, bringing the cost down to a reasonable $0.60/day.
References (7)
- 1. thorne.com
- 2. rockridgepharmacyshop.com
- 3. mamasselect.com
- 4. iherb.com
- 5. woot.com
- 6. betahealth.com.au
- 7. glimja.com